| San Severo to Settimo Torinese | 449.61 mi (723.58 km) |
| San Severo to Seveso | 414.18 mi (666.56 km) |
| San Severo to Sezze | 120.25 mi (193.52 km) |
| San Severo to Siano | 71.20 mi (114.58 km) |
| San Severo to Siena | 234.67 mi (377.67 km) |
| San Severo to Signa | 260.66 mi (419.50 km) |
| San Severo to Silea | 313.91 mi (505.19 km) |
| San Severo to Silvi Paese | 87.61 mi (140.99 km) |
| San Severo to Sinalunga | 213.51 mi (343.61 km) |
| San Severo to Siniscola | 305.64 mi (491.88 km) |
| San Severo to Sinnai | 364.05 mi (585.88 km) |
| San Severo to Siracusa | 319.66 mi (514.44 km) |
| San Severo to Solaro | 414.97 mi (667.83 km) |
| San Severo to Soliera | 307.35 mi (494.64 km) |
| San Severo to Solofra | 65.58 mi (105.55 km) |
