| San Severo to Spilamberto | 294.66 mi (474.21 km) |
| San Severo to Spilimbergo | 330.45 mi (531.81 km) |
| San Severo to Spinea | 307.84 mi (495.42 km) |
| San Severo to Spoleto | 156.11 mi (251.23 km) |
| San Severo to Spoltore | 82.44 mi (132.68 km) |
| San Severo to Spresiano | 322.72 mi (519.37 km) |
| San Severo to Squinzano | 164.18 mi (264.21 km) |
| San Severo to Statte | 122.70 mi (197.47 km) |
| San Severo to Stezzano | 395.53 mi (636.55 km) |
| San Severo to Strada | 244.21 mi (393.01 km) |
| San Severo to Stradella | 384.50 mi (618.78 km) |
| San Severo to Striano | 73.92 mi (118.97 km) |
| San Severo to Subiaco | 118.52 mi (190.74 km) |
| San Severo to Sulmona | 78.64 mi (126.55 km) |
| San Severo to Surbo | 169.10 mi (272.15 km) |
