| Sanlucar de Barrameda to Sestu | 857.26 mi (1,379.62 km) |
| Sanlucar de Barrameda to Settimo Torinese | 934.10 mi (1,503.28 km) |
| Sanlucar de Barrameda to Seveso | 1,009.11 mi (1,624.01 km) |
| Sanlucar de Barrameda to Sezze | 1,088.05 mi (1,751.05 km) |
| Sanlucar de Barrameda to Siano | 1,164.10 mi (1,873.45 km) |
| Sanlucar de Barrameda to Siena | 1,036.23 mi (1,667.65 km) |
| Sanlucar de Barrameda to Signa | 1,036.88 mi (1,668.69 km) |
| Sanlucar de Barrameda to Silea | 1,143.10 mi (1,839.64 km) |
| Sanlucar de Barrameda to Silvi Paese | 1,156.13 mi (1,860.61 km) |
| Sanlucar de Barrameda to Sinalunga | 1,052.97 mi (1,694.59 km) |
| Sanlucar de Barrameda to Siniscola | 903.20 mi (1,453.56 km) |
| Sanlucar de Barrameda to Sinnai | 863.19 mi (1,389.17 km) |
| Sanlucar de Barrameda to Siracusa | 1,192.85 mi (1,919.70 km) |
| Sanlucar de Barrameda to Solaro | 1,005.88 mi (1,618.81 km) |
| Sanlucar de Barrameda to Soliera | 1,055.44 mi (1,698.56 km) |
