| Sanlucar la Mayor to Ede | 1,165.53 mi (1,875.74 km) |
| Sanlucar la Mayor to Eemnes | 1,167.28 mi (1,878.55 km) |
| Sanlucar la Mayor to Eerbeek | 1,178.26 mi (1,896.23 km) |
| Sanlucar la Mayor to Eersel | 1,117.18 mi (1,797.93 km) |
| Sanlucar la Mayor to Eijsden | 1,095.07 mi (1,762.34 km) |
| Sanlucar la Mayor to Eindhoven | 1,126.01 mi (1,812.14 km) |
| Sanlucar la Mayor to Elburg | 1,192.76 mi (1,919.56 km) |
| Sanlucar la Mayor to Emmeloord | 1,205.39 mi (1,939.89 km) |
| Sanlucar la Mayor to Emmen | 1,236.86 mi (1,990.53 km) |
| Sanlucar la Mayor to Enkhuizen | 1,194.62 mi (1,922.55 km) |
| Sanlucar la Mayor to Enschede | 1,205.35 mi (1,939.82 km) |
| Sanlucar la Mayor to Epe | 1,190.21 mi (1,915.46 km) |
| Sanlucar la Mayor to Ermelo | 1,178.67 mi (1,896.89 km) |
| Sanlucar la Mayor to Etten-Leur | 1,113.35 mi (1,791.76 km) |
| Sanlucar la Mayor to Franeker | 1,229.05 mi (1,977.97 km) |
