| Sanlucar la Mayor to Sesimbra | 174.21 mi (280.36 km) |
| Sanlucar la Mayor to Setubal | 166.53 mi (268.01 km) |
| Sanlucar la Mayor to Sever do Vouga | 259.00 mi (416.82 km) |
| Sanlucar la Mayor to Silves | 123.82 mi (199.27 km) |
| Sanlucar la Mayor to Sines | 150.97 mi (242.96 km) |
| Sanlucar la Mayor to Sintra | 199.06 mi (320.36 km) |
| Sanlucar la Mayor to Sobrado de Paiva | 275.38 mi (443.19 km) |
| Sanlucar la Mayor to Sobral de Monte Agraco | 196.07 mi (315.55 km) |
| Sanlucar la Mayor to Soure | 226.17 mi (363.98 km) |
| Sanlucar la Mayor to Tabua | 228.01 mi (366.95 km) |
| Sanlucar la Mayor to Tavira | 81.84 mi (131.71 km) |
| Sanlucar la Mayor to Tomar | 194.49 mi (313.00 km) |
| Sanlucar la Mayor to Tondela | 238.98 mi (384.60 km) |
| Sanlucar la Mayor to Torre de Moncorvo | 268.40 mi (431.94 km) |
| Sanlucar la Mayor to Torres Novas | 191.50 mi (308.18 km) |
