| Sansepolcro to Spilamberto | 86.67 mi (139.48 km) |
| Sansepolcro to Spilimbergo | 180.06 mi (289.77 km) |
| Sansepolcro to Spinea | 132.49 mi (213.22 km) |
| Sansepolcro to Spoleto | 62.83 mi (101.12 km) |
| Sansepolcro to Spoltore | 127.13 mi (204.59 km) |
| Sansepolcro to Spresiano | 152.63 mi (245.63 km) |
| Sansepolcro to Squinzano | 372.79 mi (599.95 km) |
| Sansepolcro to Statte | 332.26 mi (534.72 km) |
| Sansepolcro to Stezzano | 188.58 mi (303.49 km) |
| Sansepolcro to Strada | 41.41 mi (66.64 km) |
| Sansepolcro to Stradella | 174.94 mi (281.53 km) |
| Sansepolcro to Striano | 227.39 mi (365.95 km) |
| Sansepolcro to Subiaco | 123.40 mi (198.60 km) |
| Sansepolcro to Sulmona | 138.92 mi (223.57 km) |
| Sansepolcro to Surbo | 377.67 mi (607.80 km) |
