| Sansepolcro to Sangeorz-Bai | 660.57 mi (1,063.09 km) |
| Sansepolcro to Sannicolau Mare | 448.94 mi (722.51 km) |
| Sansepolcro to Santana | 495.55 mi (797.51 km) |
| Sansepolcro to Satu Mare | 594.10 mi (956.11 km) |
| Sansepolcro to Scobinti | 761.80 mi (1,226.00 km) |
| Sansepolcro to Scornicesti | 619.06 mi (996.28 km) |
| Sansepolcro to Sebes | 583.61 mi (939.23 km) |
| Sansepolcro to Seini | 609.55 mi (980.98 km) |
| Sansepolcro to Sfantu-Gheorghe | 687.30 mi (1,106.10 km) |
| Sansepolcro to Sibiu | 608.80 mi (979.77 km) |
| Sansepolcro to Sighetu Marmatiei | 640.36 mi (1,030.56 km) |
| Sansepolcro to Sighisoara | 644.54 mi (1,037.29 km) |
| Sansepolcro to Simeria | 555.68 mi (894.28 km) |
| Sansepolcro to Sinaia | 671.59 mi (1,080.83 km) |
| Sansepolcro to Slatina | 609.63 mi (981.10 km) |
