| Sansepolcro to Santander | 797.89 mi (1,284.08 km) |
| Sansepolcro to Santany | 549.94 mi (885.05 km) |
| Sansepolcro to Santiago de Compostela | 1,039.97 mi (1,673.67 km) |
| Sansepolcro to Santiago del Teide | 1,918.13 mi (3,086.94 km) |
| Sansepolcro to Santiponce | 1,042.52 mi (1,677.78 km) |
| Sansepolcro to Santomera | 786.73 mi (1,266.12 km) |
| Sansepolcro to Santona | 780.71 mi (1,256.44 km) |
| Sansepolcro to Santurce-Antiguo | 760.29 mi (1,223.56 km) |
| Sansepolcro to Sarria | 984.78 mi (1,584.85 km) |
| Sansepolcro to Sauzal | 1,892.42 mi (3,045.56 km) |
| Sansepolcro to Sedavi | 707.91 mi (1,139.27 km) |
| Sansepolcro to Segorbe | 699.64 mi (1,125.97 km) |
| Sansepolcro to Segovia | 849.66 mi (1,367.39 km) |
| Sansepolcro to Senmanat | 526.53 mi (847.36 km) |
| Sansepolcro to Sesena | 848.51 mi (1,365.54 km) |
