| Santa Clara to Elyria (Ohio) | 2,128.22 mi (3,425.04 km) |
| Santa Clara to Emeryville (California) | 37.25 mi (59.95 km) |
| Santa Clara to Emmaus (Pennsylvania) | 2,477.70 mi (3,987.47 km) |
| Santa Clara to Emporia (Kansas) | 1,402.82 mi (2,257.63 km) |
| Santa Clara to Encinitas (California) | 399.27 mi (642.57 km) |
| Santa Clara to Endicott (New York) | 2,431.51 mi (3,913.13 km) |
| Santa Clara to Endwell (New York) | 2,433.45 mi (3,916.25 km) |
| Santa Clara to Englewood (Colorado) | 929.74 mi (1,496.27 km) |
| Santa Clara to Englewood (Florida) | 2,406.06 mi (3,872.19 km) |
| Santa Clara to Englewood (New Jersey) | 2,551.71 mi (4,106.57 km) |
| Santa Clara to Englewood (Ohio) | 2,025.50 mi (3,259.72 km) |
| Santa Clara to Enid (Oklahoma) | 1,329.77 mi (2,140.06 km) |
| Santa Clara to Ennis (Texas) | 1,473.25 mi (2,370.96 km) |
| Santa Clara to Ensley (Florida) | 2,031.81 mi (3,269.89 km) |
| Santa Clara to Enterprise (Alabama) | 2,089.22 mi (3,362.28 km) |
