| Santa Comba to Spello | 1,082.53 mi (1,742.16 km) |
| Santa Comba to Spilamberto | 992.09 mi (1,596.61 km) |
| Santa Comba to Spilimbergo | 1,085.36 mi (1,746.72 km) |
| Santa Comba to Spinea | 1,048.46 mi (1,687.34 km) |
| Santa Comba to Spoleto | 1,085.42 mi (1,746.81 km) |
| Santa Comba to Spoltore | 1,161.74 mi (1,869.65 km) |
| Santa Comba to Spresiano | 1,053.59 mi (1,695.59 km) |
| Santa Comba to Squinzano | 1,390.70 mi (2,238.11 km) |
| Santa Comba to Statte | 1,345.23 mi (2,164.94 km) |
| Santa Comba to Stezzano | 927.97 mi (1,493.43 km) |
| Santa Comba to Strada | 1,010.31 mi (1,625.94 km) |
| Santa Comba to Stradella | 908.43 mi (1,461.98 km) |
| Santa Comba to Striano | 1,207.67 mi (1,943.56 km) |
| Santa Comba to Subiaco | 1,116.01 mi (1,796.04 km) |
| Santa Comba to Sulmona | 1,156.09 mi (1,860.55 km) |
