| Santa Comba to Sesimbra | 317.81 mi (511.46 km) |
| Santa Comba to Setubal | 311.91 mi (501.98 km) |
| Santa Comba to Sever do Vouga | 160.91 mi (258.97 km) |
| Santa Comba to Silves | 404.78 mi (651.43 km) |
| Santa Comba to Sines | 351.25 mi (565.29 km) |
| Santa Comba to Sintra | 294.42 mi (473.82 km) |
| Santa Comba to Sobrado de Paiva | 141.35 mi (227.48 km) |
| Santa Comba to Sobral de Monte Agraco | 278.33 mi (447.93 km) |
| Santa Comba to Soure | 206.68 mi (332.62 km) |
| Santa Comba to Tabua | 189.41 mi (304.82 km) |
| Santa Comba to Tavira | 413.73 mi (665.84 km) |
| Santa Comba to Tomar | 238.46 mi (383.76 km) |
| Santa Comba to Tondela | 178.25 mi (286.86 km) |
| Santa Comba to Torre de Moncorvo | 153.46 mi (246.98 km) |
| Santa Comba to Torres Novas | 247.20 mi (397.84 km) |
