| Santa Cruz de la Palma to Selargius | 1,698.28 mi (2,733.12 km) |
| Santa Cruz de la Palma to Selvazzano Dentro | 1,978.58 mi (3,184.22 km) |
| Santa Cruz de la Palma to Senago | 1,870.96 mi (3,011.01 km) |
| Santa Cruz de la Palma to Senigallia | 1,998.06 mi (3,215.57 km) |
| Santa Cruz de la Palma to Seravezza | 1,868.91 mi (3,007.72 km) |
| Santa Cruz de la Palma to Seregno | 1,876.02 mi (3,019.17 km) |
| Santa Cruz de la Palma to Seriate | 1,899.05 mi (3,056.22 km) |
| Santa Cruz de la Palma to Sermoneta | 1,937.61 mi (3,118.29 km) |
| Santa Cruz de la Palma to Serramanna | 1,689.63 mi (2,719.20 km) |
| Santa Cruz de la Palma to Serravalle Pistoiese | 1,893.17 mi (3,046.76 km) |
| Santa Cruz de la Palma to Sessa Aurunca | 1,978.52 mi (3,184.12 km) |
| Santa Cruz de la Palma to Sesto Calende | 1,855.15 mi (2,985.58 km) |
| Santa Cruz de la Palma to Sesto Fiorentino | 1,908.01 mi (3,070.64 km) |
| Santa Cruz de la Palma to Sesto San Giovanni | 1,873.49 mi (3,015.09 km) |
| Santa Cruz de la Palma to Sestri Levante | 1,839.68 mi (2,960.67 km) |
