| Santa Cruz de la Palma to Spello | 1,954.75 mi (3,145.86 km) |
| Santa Cruz de la Palma to Spilamberto | 1,919.63 mi (3,089.35 km) |
| Santa Cruz de la Palma to Spilimbergo | 2,048.63 mi (3,296.95 km) |
| Santa Cruz de la Palma to Spinea | 1,998.36 mi (3,216.05 km) |
| Santa Cruz de la Palma to Spoleto | 1,949.86 mi (3,137.99 km) |
| Santa Cruz de la Palma to Spoltore | 2,013.13 mi (3,239.82 km) |
| Santa Cruz de la Palma to Spresiano | 2,010.85 mi (3,236.16 km) |
| Santa Cruz de la Palma to Squinzano | 2,175.41 mi (3,500.98 km) |
| Santa Cruz de la Palma to Statte | 2,133.36 mi (3,433.31 km) |
| Santa Cruz de la Palma to Stezzano | 1,895.17 mi (3,049.98 km) |
| Santa Cruz de la Palma to Strada | 1,906.54 mi (3,068.27 km) |
| Santa Cruz de la Palma to Stradella | 1,861.42 mi (2,995.67 km) |
| Santa Cruz de la Palma to Striano | 2,002.85 mi (3,223.27 km) |
| Santa Cruz de la Palma to Subiaco | 1,951.40 mi (3,140.48 km) |
| Santa Cruz de la Palma to Sulmona | 1,994.24 mi (3,209.42 km) |
