| Santander to Sacile | 817.48 mi (1,315.61 km) |
| Santander to Sala Consilina | 1,017.16 mi (1,636.96 km) |
| Santander to Salemi | 951.78 mi (1,531.74 km) |
| Santander to Salerno | 969.21 mi (1,559.79 km) |
| Santander to Salo | 720.45 mi (1,159.45 km) |
| Santander to Salsomaggiore Terme | 689.01 mi (1,108.86 km) |
| Santander to Saluzzo | 566.34 mi (911.44 km) |
| Santander to Salzano | 796.21 mi (1,281.37 km) |
| Santander to Samarate | 636.81 mi (1,024.85 km) |
| Santander to San Benedetto del Tronto | 889.84 mi (1,432.06 km) |
| Santander to San Biagio di Callalta | 809.87 mi (1,303.35 km) |
| Santander to San Bonifacio | 755.20 mi (1,215.38 km) |
| Santander to San Casciano in Val di Pesa | 749.67 mi (1,206.48 km) |
| Santander to San Cataldo | 1,019.47 mi (1,640.69 km) |
| Santander to San Cesareo | 850.16 mi (1,368.20 km) |
