| Santiago do Cacem to Sacile | 1,214.22 mi (1,954.10 km) |
| Santiago do Cacem to Sala Consilina | 1,307.15 mi (2,103.65 km) |
| Santiago do Cacem to Salemi | 1,169.39 mi (1,881.94 km) |
| Santiago do Cacem to Salerno | 1,263.04 mi (2,032.67 km) |
| Santiago do Cacem to Salo | 1,116.55 mi (1,796.92 km) |
| Santiago do Cacem to Salsomaggiore Terme | 1,072.43 mi (1,725.91 km) |
| Santiago do Cacem to Saluzzo | 954.31 mi (1,535.81 km) |
| Santiago do Cacem to Salzano | 1,187.02 mi (1,910.32 km) |
| Santiago do Cacem to Samarate | 1,038.94 mi (1,672.02 km) |
| Santiago do Cacem to San Benedetto del Tronto | 1,230.51 mi (1,980.32 km) |
| Santiago do Cacem to San Biagio di Callalta | 1,202.53 mi (1,935.28 km) |
| Santiago do Cacem to San Bonifacio | 1,145.83 mi (1,844.04 km) |
| Santiago do Cacem to San Casciano in Val di Pesa | 1,106.78 mi (1,781.19 km) |
| Santiago do Cacem to San Cataldo | 1,236.70 mi (1,990.27 km) |
| Santiago do Cacem to San Cesareo | 1,165.88 mi (1,876.30 km) |
