| Santiago do Cacem to Sestu | 962.46 mi (1,548.93 km) |
| Santiago do Cacem to Settimo Torinese | 980.24 mi (1,577.54 km) |
| Santiago do Cacem to Seveso | 1,055.33 mi (1,698.39 km) |
| Santiago do Cacem to Sezze | 1,177.59 mi (1,895.14 km) |
| Santiago do Cacem to Siano | 1,259.76 mi (2,027.39 km) |
| Santiago do Cacem to Siena | 1,108.57 mi (1,784.07 km) |
| Santiago do Cacem to Signa | 1,104.75 mi (1,777.92 km) |
| Santiago do Cacem to Silea | 1,197.94 mi (1,927.90 km) |
| Santiago do Cacem to Silvi Paese | 1,238.55 mi (1,993.25 km) |
| Santiago do Cacem to Sinalunga | 1,126.88 mi (1,813.54 km) |
| Santiago do Cacem to Siniscola | 997.49 mi (1,605.30 km) |
| Santiago do Cacem to Sinnai | 968.41 mi (1,558.50 km) |
| Santiago do Cacem to Siracusa | 1,312.12 mi (2,111.65 km) |
| Santiago do Cacem to Solaro | 1,052.18 mi (1,693.31 km) |
| Santiago do Cacem to Soliera | 1,114.66 mi (1,793.87 km) |
