| Santiago do Cacem to Spello | 1,170.48 mi (1,883.71 km) |
| Santiago do Cacem to Spilamberto | 1,114.76 mi (1,794.04 km) |
| Santiago do Cacem to Spilimbergo | 1,235.33 mi (1,988.08 km) |
| Santiago do Cacem to Spinea | 1,188.15 mi (1,912.15 km) |
| Santiago do Cacem to Spoleto | 1,168.51 mi (1,880.54 km) |
| Santiago do Cacem to Spoltore | 1,238.94 mi (1,993.88 km) |
| Santiago do Cacem to Spresiano | 1,198.69 mi (1,929.11 km) |
| Santiago do Cacem to Squinzano | 1,435.94 mi (2,310.92 km) |
| Santiago do Cacem to Statte | 1,391.04 mi (2,238.66 km) |
| Santiago do Cacem to Stezzano | 1,078.41 mi (1,735.54 km) |
| Santiago do Cacem to Strada | 1,111.95 mi (1,789.51 km) |
| Santiago do Cacem to Stradella | 1,047.78 mi (1,686.23 km) |
| Santiago do Cacem to Striano | 1,253.11 mi (2,016.68 km) |
| Santiago do Cacem to Subiaco | 1,182.06 mi (1,902.34 km) |
| Santiago do Cacem to Sulmona | 1,225.07 mi (1,971.56 km) |
