| Santurce-Antiguo to Sestu | 687.17 mi (1,105.89 km) |
| Santurce-Antiguo to Settimo Torinese | 548.45 mi (882.64 km) |
| Santurce-Antiguo to Seveso | 620.06 mi (997.89 km) |
| Santurce-Antiguo to Sezze | 829.50 mi (1,334.96 km) |
| Santurce-Antiguo to Siano | 923.97 mi (1,486.99 km) |
| Santurce-Antiguo to Siena | 721.04 mi (1,160.40 km) |
| Santurce-Antiguo to Signa | 707.41 mi (1,138.47 km) |
| Santurce-Antiguo to Silea | 771.08 mi (1,240.93 km) |
| Santurce-Antiguo to Silvi Paese | 867.51 mi (1,396.12 km) |
| Santurce-Antiguo to Sinalunga | 741.83 mi (1,193.86 km) |
| Santurce-Antiguo to Siniscola | 680.38 mi (1,094.97 km) |
| Santurce-Antiguo to Sinnai | 692.33 mi (1,114.20 km) |
| Santurce-Antiguo to Siracusa | 1,056.17 mi (1,699.74 km) |
| Santurce-Antiguo to Solaro | 617.16 mi (993.22 km) |
| Santurce-Antiguo to Soliera | 699.13 mi (1,125.15 km) |
