| Santurce-Antiguo to Smolyan | 1,412.25 mi (2,272.80 km) |
| Santurce-Antiguo to Sofia | 1,326.92 mi (2,135.48 km) |
| Santurce-Antiguo to Sopot | 1,398.36 mi (2,250.44 km) |
| Santurce-Antiguo to Sozopol | 1,548.57 mi (2,492.19 km) |
| Santurce-Antiguo to Sredets | 1,524.72 mi (2,453.81 km) |
| Santurce-Antiguo to Stamboliyski | 1,395.04 mi (2,245.09 km) |
| Santurce-Antiguo to Stara Zagora | 1,446.27 mi (2,327.55 km) |
| Santurce-Antiguo to Svilengrad | 1,484.22 mi (2,388.62 km) |
| Santurce-Antiguo to Svishtov | 1,416.22 mi (2,279.19 km) |
| Santurce-Antiguo to Targovishte | 1,481.51 mi (2,384.26 km) |
| Santurce-Antiguo to Teteven | 1,370.78 mi (2,206.06 km) |
| Santurce-Antiguo to Troyan | 1,393.59 mi (2,242.76 km) |
| Santurce-Antiguo to Tryavna | 1,432.74 mi (2,305.77 km) |
| Santurce-Antiguo to Tutrakan | 1,474.05 mi (2,372.25 km) |
| Santurce-Antiguo to Varna | 1,547.88 mi (2,491.08 km) |
