| Sebring to Enterprise (Nevada) | 2,058.62 mi (3,313.03 km) |
| Sebring to Enumclaw (Washington) | 2,569.47 mi (4,135.17 km) |
| Sebring to Ephrata (Pennsylvania) | 927.97 mi (1,493.42 km) |
| Sebring to Erie (Colorado) | 1,601.22 mi (2,576.91 km) |
| Sebring to Erie (Pennsylvania) | 1,014.49 mi (1,632.66 km) |
| Sebring to Erlanger (Kentucky) | 817.07 mi (1,314.95 km) |
| Sebring to Escanaba (Michigan) | 1,299.66 mi (2,091.60 km) |
| Sebring to Escondido (California) | 2,149.85 mi (3,459.85 km) |
| Sebring to Española (New Mexico) | 1,556.24 mi (2,504.52 km) |
| Sebring to Essex (Maryland) | 866.21 mi (1,394.03 km) |
| Sebring to Essex Junction (Vermont) | 1,262.89 mi (2,032.42 km) |
| Sebring to Estelle (Louisiana) | 549.12 mi (883.73 km) |
| Sebring to Estero (Florida) | 75.51 mi (121.51 km) |
| Sebring to Euclid (Ohio) | 975.14 mi (1,569.34 km) |
| Sebring to Eufaula (Alabama) | 378.18 mi (608.62 km) |
