| Senigallia to Sacile | 159.63 mi (256.91 km) |
| Senigallia to Sala Consilina | 259.45 mi (417.55 km) |
| Senigallia to Salemi | 407.99 mi (656.59 km) |
| Senigallia to Salerno | 223.88 mi (360.30 km) |
| Senigallia to Salo | 185.48 mi (298.50 km) |
| Senigallia to Salsomaggiore Terme | 177.39 mi (285.49 km) |
| Senigallia to Saluzzo | 290.96 mi (468.26 km) |
| Senigallia to Salzano | 136.93 mi (220.37 km) |
| Senigallia to Samarate | 254.50 mi (409.57 km) |
| Senigallia to San Benedetto del Tronto | 62.42 mi (100.46 km) |
| Senigallia to San Biagio di Callalta | 142.42 mi (229.20 km) |
| Senigallia to San Bonifacio | 150.52 mi (242.24 km) |
| Senigallia to San Casciano in Val di Pesa | 101.62 mi (163.55 km) |
| Senigallia to San Cataldo | 432.30 mi (695.72 km) |
| Senigallia to San Cesareo | 132.73 mi (213.62 km) |
