| Senigallia to Somma Lombardo | 260.27 mi (418.87 km) |
| Senigallia to Somma Vesuviana | 205.90 mi (331.37 km) |
| Senigallia to Sommacampagna | 164.85 mi (265.30 km) |
| Senigallia to Sona | 167.04 mi (268.82 km) |
| Senigallia to Sondrio | 235.81 mi (379.49 km) |
| Senigallia to Sora | 139.41 mi (224.36 km) |
| Senigallia to Sorbolo | 157.79 mi (253.94 km) |
| Senigallia to Soresina | 198.11 mi (318.82 km) |
| Senigallia to Sorisole | 223.88 mi (360.29 km) |
| Senigallia to Sorrento | 221.22 mi (356.03 km) |
| Senigallia to Sorso | 311.18 mi (500.80 km) |
| Senigallia to Sortino | 462.24 mi (743.90 km) |
| Senigallia to Soverato Marina | 388.21 mi (624.77 km) |
| Senigallia to Sovicille | 103.82 mi (167.09 km) |
| Senigallia to Spello | 57.07 mi (91.84 km) |
