| Senigallia to Spilamberto | 123.02 mi (197.98 km) |
| Senigallia to Spilimbergo | 167.65 mi (269.81 km) |
| Senigallia to Spinea | 133.54 mi (214.91 km) |
| Senigallia to Spoleto | 71.33 mi (114.79 km) |
| Senigallia to Spoltore | 98.58 mi (158.65 km) |
| Senigallia to Spresiano | 150.72 mi (242.56 km) |
| Senigallia to Squinzano | 335.69 mi (540.24 km) |
| Senigallia to Statte | 298.05 mi (479.66 km) |
| Senigallia to Stezzano | 220.43 mi (354.75 km) |
| Senigallia to Strada | 95.49 mi (153.68 km) |
| Senigallia to Stradella | 215.33 mi (346.53 km) |
| Senigallia to Striano | 211.66 mi (340.63 km) |
| Senigallia to Subiaco | 123.12 mi (198.14 km) |
| Senigallia to Sulmona | 120.50 mi (193.93 km) |
| Senigallia to Surbo | 340.44 mi (547.88 km) |
