| Serpa to Sestu | 904.53 mi (1,455.70 km) |
| Serpa to Settimo Torinese | 934.73 mi (1,504.31 km) |
| Serpa to Seveso | 1,009.97 mi (1,625.40 km) |
| Serpa to Sezze | 1,122.45 mi (1,806.41 km) |
| Serpa to Siano | 1,203.59 mi (1,936.99 km) |
| Serpa to Siena | 1,056.89 mi (1,700.90 km) |
| Serpa to Signa | 1,054.08 mi (1,696.37 km) |
| Serpa to Silea | 1,150.58 mi (1,851.69 km) |
| Serpa to Silvi Paese | 1,184.87 mi (1,906.86 km) |
| Serpa to Sinalunga | 1,074.88 mi (1,729.85 km) |
| Serpa to Siniscola | 941.30 mi (1,514.88 km) |
| Serpa to Sinnai | 910.49 mi (1,465.28 km) |
| Serpa to Siracusa | 1,252.72 mi (2,016.05 km) |
| Serpa to Solaro | 1,006.79 mi (1,620.27 km) |
| Serpa to Soliera | 1,066.07 mi (1,715.67 km) |
