| Sesto Fiorentino to Settimo Torinese | 191.58 mi (308.32 km) |
| Sesto Fiorentino to Seveso | 160.89 mi (258.92 km) |
| Sesto Fiorentino to Sezze | 187.03 mi (300.99 km) |
| Sesto Fiorentino to Siano | 275.12 mi (442.77 km) |
| Sesto Fiorentino to Siena | 36.19 mi (58.24 km) |
| Sesto Fiorentino to Signa | 6.07 mi (9.76 km) |
| Sesto Fiorentino to Silea | 136.87 mi (220.27 km) |
| Sesto Fiorentino to Silvi Paese | 171.59 mi (276.15 km) |
| Sesto Fiorentino to Sinalunga | 50.29 mi (80.93 km) |
| Sesto Fiorentino to Siniscola | 237.95 mi (382.95 km) |
| Sesto Fiorentino to Sinnai | 329.59 mi (530.43 km) |
| Sesto Fiorentino to Siracusa | 514.22 mi (827.56 km) |
| Sesto Fiorentino to Solaro | 161.06 mi (259.21 km) |
| Sesto Fiorentino to Soliera | 63.98 mi (102.97 km) |
| Sesto Fiorentino to Solofra | 278.73 mi (448.57 km) |
