| Setubal to Orbetello | 1,087.80 mi (1,750.65 km) |
| Setubal to Oria | 1,415.17 mi (2,277.50 km) |
| Setubal to Oristano | 939.30 mi (1,511.66 km) |
| Setubal to Orta Nova | 1,313.45 mi (2,113.80 km) |
| Setubal to Orte | 1,147.35 mi (1,846.49 km) |
| Setubal to Ortona | 1,248.90 mi (2,009.91 km) |
| Setubal to Orvieto | 1,135.64 mi (1,827.64 km) |
| Setubal to Orzinuovi | 1,074.04 mi (1,728.50 km) |
| Setubal to Osimo | 1,211.77 mi (1,950.16 km) |
| Setubal to Ospitaletto | 1,084.05 mi (1,744.61 km) |
| Setubal to Ostuni | 1,411.77 mi (2,272.02 km) |
| Setubal to Ottaviano | 1,249.17 mi (2,010.34 km) |
| Setubal to Ovada | 997.35 mi (1,605.08 km) |
| Setubal to Ozieri | 962.21 mi (1,548.52 km) |
| Setubal to Paceco | 1,161.38 mi (1,869.07 km) |
