| Setubal to Sestu | 966.77 mi (1,555.87 km) |
| Setubal to Settimo Torinese | 969.05 mi (1,559.54 km) |
| Setubal to Seveso | 1,043.92 mi (1,680.03 km) |
| Setubal to Sezze | 1,176.80 mi (1,893.87 km) |
| Setubal to Siano | 1,260.53 mi (2,028.62 km) |
| Setubal to Siena | 1,103.37 mi (1,775.70 km) |
| Setubal to Signa | 1,098.42 mi (1,767.74 km) |
| Setubal to Silea | 1,188.18 mi (1,912.20 km) |
| Setubal to Silvi Paese | 1,235.67 mi (1,988.62 km) |
| Setubal to Sinalunga | 1,122.03 mi (1,805.73 km) |
| Setubal to Siniscola | 998.51 mi (1,606.95 km) |
| Setubal to Sinnai | 972.71 mi (1,565.42 km) |
| Setubal to Siracusa | 1,320.17 mi (2,124.61 km) |
| Setubal to Solaro | 1,040.79 mi (1,675.00 km) |
| Setubal to Soliera | 1,106.17 mi (1,780.20 km) |
