| Setubal to Spello | 1,166.39 mi (1,877.13 km) |
| Setubal to Spilamberto | 1,106.75 mi (1,781.14 km) |
| Setubal to Spilimbergo | 1,224.92 mi (1,971.32 km) |
| Setubal to Spinea | 1,178.65 mi (1,896.86 km) |
| Setubal to Spoleto | 1,164.93 mi (1,874.77 km) |
| Setubal to Spoltore | 1,236.27 mi (1,989.58 km) |
| Setubal to Spresiano | 1,188.66 mi (1,912.96 km) |
| Setubal to Squinzano | 1,437.30 mi (2,313.12 km) |
| Setubal to Statte | 1,392.21 mi (2,240.55 km) |
| Setubal to Stezzano | 1,067.30 mi (1,717.65 km) |
| Setubal to Strada | 1,106.15 mi (1,780.17 km) |
| Setubal to Stradella | 1,037.68 mi (1,669.99 km) |
| Setubal to Striano | 1,253.84 mi (2,017.86 km) |
| Setubal to Subiaco | 1,180.33 mi (1,899.56 km) |
| Setubal to Sulmona | 1,223.21 mi (1,968.57 km) |
