| Seymour to Elyria (Ohio) | 260.91 mi (419.89 km) |
| Seymour to Emeryville (California) | 1,959.62 mi (3,153.70 km) |
| Seymour to Emmaus (Pennsylvania) | 562.61 mi (905.44 km) |
| Seymour to Emporia (Kansas) | 556.68 mi (895.89 km) |
| Seymour to Encinitas (California) | 1,790.80 mi (2,882.02 km) |
| Seymour to Endicott (New York) | 559.72 mi (900.78 km) |
| Seymour to Endwell (New York) | 562.22 mi (904.81 km) |
| Seymour to Englewood (Colorado) | 1,020.65 mi (1,642.57 km) |
| Seymour to Englewood (Florida) | 852.30 mi (1,371.64 km) |
| Seymour to Englewood (New Jersey) | 645.09 mi (1,038.18 km) |
| Seymour to Englewood (Ohio) | 105.65 mi (170.04 km) |
| Seymour to Enid (Oklahoma) | 677.62 mi (1,090.52 km) |
| Seymour to Ennis (Texas) | 756.26 mi (1,217.08 km) |
| Seymour to Ensley (Florida) | 587.13 mi (944.89 km) |
| Seymour to Enterprise (Alabama) | 526.50 mi (847.33 km) |
