| Seymour to Oskaloosa (Iowa) | 391.52 mi (630.10 km) |
| Seymour to Oswego (Illinois) | 228.75 mi (368.14 km) |
| Seymour to Oswego (New York) | 578.39 mi (930.83 km) |
| Seymour to Otsego (Minnesota) | 588.98 mi (947.87 km) |
| Seymour to Ottawa (Illinois) | 227.36 mi (365.89 km) |
| Seymour to Ottawa (Kansas) | 505.22 mi (813.07 km) |
| Seymour to Ottumwa (Iowa) | 373.93 mi (601.78 km) |
| Seymour to Overland (Missouri) | 241.64 mi (388.88 km) |
| Seymour to Overland Park (Kansas) | 472.69 mi (760.72 km) |
| Seymour to Overlea (Maryland) | 502.81 mi (809.19 km) |
| Seymour to Oviedo (Florida) | 760.20 mi (1,223.42 km) |
| Seymour to Owasso (Oklahoma) | 573.84 mi (923.50 km) |
| Seymour to Owatonna (Minnesota) | 519.69 mi (836.36 km) |
| Seymour to Owensboro (Kentucky) | 105.71 mi (170.12 km) |
| Seymour to Owings Mills (Maryland) | 488.22 mi (785.72 km) |
