| Seymour to Scottsbluff (Nebraska) | 954.59 mi (1,536.27 km) |
| Seymour to Scottsboro (Alabama) | 297.49 mi (478.77 km) |
| Seymour to Scottsdale (Arizona) | 1,485.44 mi (2,390.58 km) |
| Seymour to Scranton (Pennsylvania) | 565.51 mi (910.10 km) |
| Seymour to Seabrook (Maryland) | 485.51 mi (781.35 km) |
| Seymour to Seabrook (Texas) | 830.47 mi (1,336.51 km) |
| Seymour to Seaford (New York) | 668.15 mi (1,075.29 km) |
| Seymour to Seagoville (Texas) | 737.81 mi (1,187.39 km) |
| Seymour to Seal Beach (California) | 1,816.51 mi (2,923.39 km) |
| Seymour to Searcy (Arkansas) | 411.29 mi (661.91 km) |
| Seymour to Seaside (California) | 1,955.79 mi (3,147.55 km) |
| Seymour to SeaTac (Washington) | 1,905.62 mi (3,066.80 km) |
| Seymour to Seattle (Washington) | 1,907.80 mi (3,070.31 km) |
| Seymour to Sebastian (Florida) | 831.77 mi (1,338.60 km) |
| Seymour to Sebring (Florida) | 832.72 mi (1,340.14 km) |
