| Seymour to Southern Pines (North Carolina) | 441.63 mi (710.74 km) |
| Seymour to Southfield (Michigan) | 280.02 mi (450.65 km) |
| Seymour to Southgate (Michigan) | 265.49 mi (427.27 km) |
| Seymour to Southlake (Texas) | 752.78 mi (1,211.48 km) |
| Seymour to Spanaway (Washington) | 1,909.75 mi (3,073.45 km) |
| Seymour to Spanish Fork (Utah) | 1,369.79 mi (2,204.47 km) |
| Seymour to Spanish Lake (Missouri) | 232.45 mi (374.10 km) |
| Seymour to Spanish Springs (Nevada) | 1,795.91 mi (2,890.24 km) |
| Seymour to Sparks (Nevada) | 1,799.31 mi (2,895.71 km) |
| Seymour to Spartanburg (South Carolina) | 352.72 mi (567.65 km) |
| Seymour to Spearfish (South Dakota) | 997.93 mi (1,606.01 km) |
| Seymour to Speedway (Indiana) | 61.49 mi (98.96 km) |
| Seymour to Spencer (Iowa) | 562.64 mi (905.48 km) |
| Seymour to Spokane (Washington) | 1,682.24 mi (2,707.30 km) |
| Seymour to Spokane Valley (Washington) | 1,673.08 mi (2,692.56 km) |
