| Seymour to Superior (Colorado) | 1,028.37 mi (1,655.00 km) |
| Seymour to Superior (Wisconsin) | 619.95 mi (997.71 km) |
| Seymour to Surprise (Arizona) | 1,516.93 mi (2,441.26 km) |
| Seymour to Susanville (California) | 1,837.18 mi (2,956.65 km) |
| Seymour to Sussex (Wisconsin) | 313.74 mi (504.91 km) |
| Seymour to Suwanee (Georgia) | 353.13 mi (568.31 km) |
| Seymour to Swansea (Illinois) | 222.32 mi (357.79 km) |
| Seymour to Sweetwater (Florida) | 964.61 mi (1,552.40 km) |
| Seymour to Sweetwater (Texas) | 927.78 mi (1,493.12 km) |
| Seymour to Sycamore (Illinois) | 256.62 mi (413.00 km) |
| Seymour to Sylacauga (Alabama) | 399.17 mi (642.41 km) |
| Seymour to Sylvania (Ohio) | 222.77 mi (358.52 km) |
| Seymour to Syosset (New York) | 668.83 mi (1,076.37 km) |
| Seymour to Syracuse (New York) | 581.16 mi (935.29 km) |
| Seymour to Syracuse (Utah) | 1,387.86 mi (2,233.54 km) |
