| Sheffield to Sestu | 1,092.95 mi (1,758.93 km) |
| Sheffield to Settimo Torinese | 704.63 mi (1,133.99 km) |
| Sheffield to Seveso | 714.23 mi (1,149.44 km) |
| Sheffield to Sezze | 1,061.35 mi (1,708.07 km) |
| Sheffield to Siano | 1,149.36 mi (1,849.72 km) |
| Sheffield to Siena | 907.67 mi (1,460.75 km) |
| Sheffield to Signa | 874.85 mi (1,407.94 km) |
| Sheffield to Silea | 813.82 mi (1,309.71 km) |
| Sheffield to Silvi Paese | 1,034.87 mi (1,665.46 km) |
| Sheffield to Sinalunga | 925.19 mi (1,488.94 km) |
| Sheffield to Siniscola | 1,026.86 mi (1,652.57 km) |
| Sheffield to Sinnai | 1,095.15 mi (1,762.47 km) |
| Sheffield to Siracusa | 1,383.68 mi (2,226.81 km) |
| Sheffield to Solaro | 714.20 mi (1,149.40 km) |
| Sheffield to Soliera | 817.21 mi (1,315.17 km) |
