| Sheffield to Stonehaven | 249.29 mi (401.19 km) |
| Sheffield to Stourbridge | 69.76 mi (112.27 km) |
| Sheffield to Stowmarket | 131.99 mi (212.42 km) |
| Sheffield to Stranraer | 178.21 mi (286.79 km) |
| Sheffield to Stratford | 141.25 mi (227.32 km) |
| Sheffield to Stratford-upon-Avon | 82.67 mi (133.05 km) |
| Sheffield to Stratton Saint Margaret | 124.61 mi (200.55 km) |
| Sheffield to Streatham | 146.38 mi (235.58 km) |
| Sheffield to Street | 164.92 mi (265.41 km) |
| Sheffield to Streetly | 58.14 mi (93.57 km) |
| Sheffield to Stretford | 34.82 mi (56.04 km) |
| Sheffield to Strood | 160.03 mi (257.54 km) |
| Sheffield to Stroud | 117.34 mi (188.83 km) |
| Sheffield to Sudbury | 135.20 mi (217.59 km) |
| Sheffield to Sudbury | 130.49 mi (210.00 km) |
