| Shoreham-by-Sea to Sacile | 674.26 mi (1,085.11 km) |
| Shoreham-by-Sea to Sala Consilina | 1,048.58 mi (1,687.52 km) |
| Shoreham-by-Sea to Salemi | 1,103.92 mi (1,776.58 km) |
| Shoreham-by-Sea to Salerno | 1,005.00 mi (1,617.39 km) |
| Shoreham-by-Sea to Salo | 614.05 mi (988.22 km) |
| Shoreham-by-Sea to Salsomaggiore Terme | 630.77 mi (1,015.12 km) |
| Shoreham-by-Sea to Saluzzo | 558.82 mi (899.33 km) |
| Shoreham-by-Sea to Salzano | 676.83 mi (1,089.25 km) |
| Shoreham-by-Sea to Samarate | 550.41 mi (885.79 km) |
| Shoreham-by-Sea to San Benedetto del Tronto | 859.75 mi (1,383.64 km) |
| Shoreham-by-Sea to San Biagio di Callalta | 680.78 mi (1,095.60 km) |
| Shoreham-by-Sea to San Bonifacio | 650.83 mi (1,047.41 km) |
| Shoreham-by-Sea to San Casciano in Val di Pesa | 729.77 mi (1,174.44 km) |
| Shoreham-by-Sea to San Cataldo | 1,157.73 mi (1,863.19 km) |
| Shoreham-by-Sea to San Cesareo | 879.15 mi (1,414.86 km) |
