| Shrewsbury to Sacile | 827.18 mi (1,331.22 km) |
| Shrewsbury to Sala Consilina | 1,211.41 mi (1,949.57 km) |
| Shrewsbury to Salemi | 1,271.18 mi (2,045.77 km) |
| Shrewsbury to Salerno | 1,168.55 mi (1,880.60 km) |
| Shrewsbury to Salo | 773.61 mi (1,245.01 km) |
| Shrewsbury to Salsomaggiore Terme | 793.97 mi (1,277.77 km) |
| Shrewsbury to Saluzzo | 725.74 mi (1,167.97 km) |
| Shrewsbury to Salzano | 832.77 mi (1,340.22 km) |
| Shrewsbury to Samarate | 713.81 mi (1,148.76 km) |
| Shrewsbury to San Benedetto del Tronto | 1,020.35 mi (1,642.10 km) |
| Shrewsbury to San Biagio di Callalta | 835.36 mi (1,344.39 km) |
| Shrewsbury to San Bonifacio | 809.37 mi (1,302.55 km) |
| Shrewsbury to San Casciano in Val di Pesa | 893.47 mi (1,437.90 km) |
| Shrewsbury to San Cataldo | 1,324.68 mi (2,131.86 km) |
| Shrewsbury to San Cesareo | 1,043.64 mi (1,679.58 km) |
