| Sighisoara to Sacile | 588.61 mi (947.28 km) |
| Sighisoara to Sala Consilina | 611.70 mi (984.44 km) |
| Sighisoara to Salemi | 844.27 mi (1,358.72 km) |
| Sighisoara to Salerno | 631.26 mi (1,015.91 km) |
| Sighisoara to Salo | 685.85 mi (1,103.77 km) |
| Sighisoara to Salsomaggiore Terme | 722.52 mi (1,162.79 km) |
| Sighisoara to Saluzzo | 844.14 mi (1,358.51 km) |
| Sighisoara to Salzano | 610.87 mi (983.10 km) |
| Sighisoara to Samarate | 769.28 mi (1,238.03 km) |
| Sighisoara to San Benedetto del Tronto | 581.67 mi (936.11 km) |
| Sighisoara to San Biagio di Callalta | 596.65 mi (960.21 km) |
| Sighisoara to San Bonifacio | 652.21 mi (1,049.63 km) |
| Sighisoara to San Casciano in Val di Pesa | 687.57 mi (1,106.54 km) |
| Sighisoara to San Cataldo | 819.20 mi (1,318.38 km) |
| Sighisoara to San Cesareo | 667.93 mi (1,074.93 km) |
