| Sighisoara to Sestu | 926.36 mi (1,490.84 km) |
| Sighisoara to Settimo Torinese | 823.70 mi (1,325.61 km) |
| Sighisoara to Seveso | 752.09 mi (1,210.37 km) |
| Sighisoara to Sezze | 667.91 mi (1,074.89 km) |
| Sighisoara to Siano | 628.42 mi (1,011.35 km) |
| Sighisoara to Siena | 688.97 mi (1,108.79 km) |
| Sighisoara to Signa | 688.74 mi (1,108.42 km) |
| Sighisoara to Silea | 601.01 mi (967.23 km) |
| Sighisoara to Silvi Paese | 584.17 mi (940.13 km) |
| Sighisoara to Sinalunga | 672.85 mi (1,082.85 km) |
| Sighisoara to Siniscola | 850.31 mi (1,368.44 km) |
| Sighisoara to Sinnai | 921.43 mi (1,482.90 km) |
| Sighisoara to Siracusa | 798.94 mi (1,285.76 km) |
| Sighisoara to Solaro | 754.94 mi (1,214.96 km) |
| Sighisoara to Soliera | 678.63 mi (1,092.14 km) |
