| Signa to Sacile | 165.69 mi (266.66 km) |
| Signa to Sala Consilina | 328.35 mi (528.43 km) |
| Signa to Salemi | 421.70 mi (678.67 km) |
| Signa to Salerno | 284.56 mi (457.96 km) |
| Signa to Salo | 128.57 mi (206.91 km) |
| Signa to Salsomaggiore Terme | 90.27 mi (145.28 km) |
| Signa to Saluzzo | 188.39 mi (303.18 km) |
| Signa to Salzano | 130.83 mi (210.55 km) |
| Signa to Samarate | 170.25 mi (274.00 km) |
| Signa to San Benedetto del Tronto | 151.18 mi (243.31 km) |
| Signa to San Biagio di Callalta | 145.77 mi (234.60 km) |
| Signa to San Bonifacio | 112.07 mi (180.35 km) |
| Signa to San Casciano in Val di Pesa | 9.73 mi (15.66 km) |
| Signa to San Cataldo | 460.71 mi (741.45 km) |
| Signa to San Cesareo | 160.90 mi (258.94 km) |
