| Signa to Selargius | 328.63 mi (528.87 km) |
| Signa to Selvazzano Dentro | 115.55 mi (185.96 km) |
| Signa to Senago | 157.48 mi (253.43 km) |
| Signa to Senigallia | 105.84 mi (170.33 km) |
| Signa to Seravezza | 45.68 mi (73.51 km) |
| Signa to Seregno | 159.17 mi (256.15 km) |
| Signa to Seriate | 147.85 mi (237.94 km) |
| Signa to Sermoneta | 181.55 mi (292.18 km) |
| Signa to Serramanna | 321.58 mi (517.54 km) |
| Signa to Serravalle Pistoiese | 15.55 mi (25.02 km) |
| Signa to Sessa Aurunca | 227.71 mi (366.47 km) |
| Signa to Sesto Calende | 181.09 mi (291.43 km) |
| Signa to Sesto Fiorentino | 6.07 mi (9.76 km) |
| Signa to Sesto San Giovanni | 151.77 mi (244.25 km) |
| Signa to Sestri Levante | 91.30 mi (146.93 km) |
