| Signa to Santiago do Cacem | 1,104.75 mi (1,777.92 km) |
| Signa to Santo Andre | 1,106.11 mi (1,780.11 km) |
| Signa to Santo Tirso | 1,007.64 mi (1,621.64 km) |
| Signa to Sao Bras de Alportel | 1,094.70 mi (1,761.76 km) |
| Signa to Sao Felix da Marinha | 1,021.38 mi (1,643.76 km) |
| Signa to Sao Joao da Madeira | 1,017.56 mi (1,637.60 km) |
| Signa to Sao Joao de Ver | 1,019.46 mi (1,640.66 km) |
| Signa to Sao Mamede de Infesta | 1,016.89 mi (1,636.52 km) |
| Signa to Sao Pedro do Sul | 999.74 mi (1,608.93 km) |
| Signa to Satao | 983.56 mi (1,582.89 km) |
| Signa to Seia | 989.10 mi (1,591.79 km) |
| Signa to Senhora da Hora | 1,019.71 mi (1,641.06 km) |
| Signa to Serpa | 1,054.08 mi (1,696.37 km) |
| Signa to Serta | 1,024.00 mi (1,647.98 km) |
| Signa to Sesimbra | 1,110.92 mi (1,787.86 km) |
