| Signa to Setubal | 1,098.42 mi (1,767.74 km) |
| Signa to Sever do Vouga | 1,015.01 mi (1,633.49 km) |
| Signa to Silves | 1,119.80 mi (1,802.15 km) |
| Signa to Sines | 1,114.67 mi (1,793.89 km) |
| Signa to Sintra | 1,114.57 mi (1,793.73 km) |
| Signa to Sobrado de Paiva | 1,003.67 mi (1,615.25 km) |
| Signa to Sobral de Monte Agraco | 1,096.77 mi (1,765.09 km) |
| Signa to Soure | 1,044.06 mi (1,680.25 km) |
| Signa to Tabua | 1,006.72 mi (1,620.16 km) |
| Signa to Tavira | 1,084.85 mi (1,745.89 km) |
| Signa to Tomar | 1,044.80 mi (1,681.45 km) |
| Signa to Tondela | 1,005.78 mi (1,618.64 km) |
| Signa to Torre de Moncorvo | 943.90 mi (1,519.06 km) |
| Signa to Torres Novas | 1,054.08 mi (1,696.38 km) |
| Signa to Torres Vedras | 1,100.58 mi (1,771.21 km) |
