| Signa to Sabinanigo | 583.96 mi (939.80 km) |
| Signa to Sagunto | 650.72 mi (1,047.24 km) |
| Signa to Salamanca | 875.93 mi (1,409.67 km) |
| Signa to Salobrena | 912.25 mi (1,468.13 km) |
| Signa to Salou | 541.16 mi (870.92 km) |
| Signa to Salt | 438.75 mi (706.09 km) |
| Signa to Salvatierra de Mino | 996.06 mi (1,603.00 km) |
| Signa to Sama | 839.80 mi (1,351.52 km) |
| Signa to San Adrian de Besos | 479.73 mi (772.05 km) |
| Signa to San Agustin de Guadalix | 781.58 mi (1,257.83 km) |
| Signa to San Andres de la Barca | 490.83 mi (789.91 km) |
| Signa to San Andres de Llevaneras | 463.31 mi (745.63 km) |
| Signa to San Andres del Rabanedo | 843.53 mi (1,357.53 km) |
| Signa to San Bartolome | 1,838.70 mi (2,959.10 km) |
| Signa to San Baudilio de Llobregat | 490.44 mi (789.29 km) |
