| Signa to Emeryville (California) | 6,088.73 mi (9,798.86 km) |
| Signa to Emmaus (Pennsylvania) | 4,226.22 mi (6,801.45 km) |
| Signa to Emporia (Kansas) | 5,170.45 mi (8,321.03 km) |
| Signa to Encinitas (California) | 6,211.32 mi (9,996.16 km) |
| Signa to Endicott (New York) | 4,189.44 mi (6,742.26 km) |
| Signa to Endwell (New York) | 4,186.87 mi (6,738.12 km) |
| Signa to Englewood (Colorado) | 5,433.49 mi (8,744.35 km) |
| Signa to Englewood (Florida) | 5,115.20 mi (8,232.12 km) |
| Signa to Englewood (New Jersey) | 4,146.38 mi (6,672.95 km) |
| Signa to Englewood (Ohio) | 4,626.84 mi (7,446.18 km) |
| Signa to Enid (Oklahoma) | 5,333.06 mi (8,582.72 km) |
| Signa to Ennis (Texas) | 5,485.17 mi (8,827.52 km) |
| Signa to Ensley (Florida) | 5,173.51 mi (8,325.96 km) |
| Signa to Enterprise (Alabama) | 5,073.58 mi (8,165.14 km) |
| Signa to Enterprise (Nevada) | 5,977.45 mi (9,619.78 km) |
