| Signa to Seymour (Tennessee) | 4,777.95 mi (7,689.37 km) |
| Signa to Shady Hills (Florida) | 5,058.79 mi (8,141.33 km) |
| Signa to Shafter (California) | 6,133.91 mi (9,871.58 km) |
| Signa to Shaker Heights (Ohio) | 4,444.49 mi (7,152.72 km) |
| Signa to Shakopee (Minnesota) | 4,767.51 mi (7,672.57 km) |
| Signa to Sharon (Pennsylvania) | 4,410.74 mi (7,098.40 km) |
| Signa to Sharonville (Ohio) | 4,656.17 mi (7,493.38 km) |
| Signa to Shasta Lake (California) | 5,924.04 mi (9,533.83 km) |
| Signa to Shawnee (Kansas) | 5,087.30 mi (8,187.22 km) |
| Signa to Shawnee (Oklahoma) | 5,349.34 mi (8,608.92 km) |
| Signa to Sheboygan (Wisconsin) | 4,596.58 mi (7,397.49 km) |
| Signa to Shelby (North Carolina) | 4,707.13 mi (7,575.39 km) |
| Signa to Shelbyville (Indiana) | 4,701.96 mi (7,567.08 km) |
| Signa to Shelbyville (Kentucky) | 4,737.49 mi (7,624.25 km) |
| Signa to Shelbyville (Tennessee) | 4,909.89 mi (7,901.70 km) |
