| Signa to Southern Pines (North Carolina) | 4,616.94 mi (7,430.25 km) |
| Signa to Southfield (Michigan) | 4,472.92 mi (7,198.47 km) |
| Signa to Southgate (Michigan) | 4,482.07 mi (7,213.19 km) |
| Signa to Southlake (Texas) | 5,475.04 mi (8,811.22 km) |
| Signa to Spanaway (Washington) | 5,548.55 mi (8,929.53 km) |
| Signa to Spanish Fork (Utah) | 5,633.72 mi (9,066.60 km) |
| Signa to Spanish Lake (Missouri) | 4,915.88 mi (7,911.35 km) |
| Signa to Spanish Springs (Nevada) | 5,906.84 mi (9,506.14 km) |
| Signa to Sparks (Nevada) | 5,913.01 mi (9,516.07 km) |
| Signa to Spartanburg (South Carolina) | 4,738.88 mi (7,626.49 km) |
| Signa to Spearfish (South Dakota) | 5,144.59 mi (8,279.41 km) |
| Signa to Speedway (Indiana) | 4,709.86 mi (7,579.79 km) |
| Signa to Spencer (Iowa) | 4,904.81 mi (7,893.53 km) |
| Signa to Spokane (Washington) | 5,386.39 mi (8,668.56 km) |
| Signa to Spokane Valley (Washington) | 5,381.31 mi (8,660.38 km) |
