| Sikeston to Abilene (Texas) | 652.51 mi (1,050.11 km) |
| Sikeston to Accokeek (Maryland) | 697.72 mi (1,122.87 km) |
| Sikeston to Acworth (Georgia) | 338.63 mi (544.97 km) |
| Sikeston to Ada (Oklahoma) | 422.68 mi (680.23 km) |
| Sikeston to Addison (Illinois) | 358.67 mi (577.22 km) |
| Sikeston to Addison (Texas) | 491.89 mi (791.62 km) |
| Sikeston to Adelanto (California) | 1,564.63 mi (2,518.03 km) |
| Sikeston to Adelphi (Maryland) | 702.54 mi (1,130.63 km) |
| Sikeston to Adrian (Michigan) | 455.44 mi (732.95 km) |
| Sikeston to Affton (Missouri) | 121.89 mi (196.16 km) |
| Sikeston to Agoura Hills (California) | 1,645.03 mi (2,647.42 km) |
| Sikeston to Aguadilla (Puerto Rico) | 1,863.91 mi (2,999.67 km) |
| Sikeston to Aiken (South Carolina) | 500.42 mi (805.35 km) |
| Sikeston to Akron (Ohio) | 520.85 mi (838.22 km) |
| Sikeston to Alabaster (Alabama) | 297.63 mi (478.99 km) |
