| Sikeston to Ashtabula (Ohio) | 582.10 mi (936.79 km) |
| Sikeston to Ashwaubenon (Wisconsin) | 530.52 mi (853.80 km) |
| Sikeston to Aspen Hill (Maryland) | 697.21 mi (1,122.05 km) |
| Sikeston to Astoria (Oregon) | 1,865.52 mi (3,002.27 km) |
| Sikeston to Atascadero (California) | 1,729.29 mi (2,783.03 km) |
| Sikeston to Atascocita (Texas) | 576.22 mi (927.33 km) |
| Sikeston to Atchison (Kansas) | 353.35 mi (568.67 km) |
| Sikeston to Athens (Alabama) | 207.10 mi (333.30 km) |
| Sikeston to Athens (Georgia) | 404.50 mi (650.98 km) |
| Sikeston to Athens (Ohio) | 440.54 mi (708.98 km) |
| Sikeston to Athens (Tennessee) | 294.89 mi (474.58 km) |
| Sikeston to Athens (Texas) | 480.31 mi (772.99 km) |
| Sikeston to Atlanta (Georgia) | 362.32 mi (583.10 km) |
| Sikeston to Atlantic Beach (Florida) | 652.14 mi (1,049.51 km) |
| Sikeston to Atlantic City (New Jersey) | 839.34 mi (1,350.78 km) |
