| Sikeston to Cadillac (Michigan) | 553.70 mi (891.10 km) |
| Sikeston to Caguas (Puerto Rico) | 1,924.00 mi (3,096.38 km) |
| Sikeston to Cahokia (Illinois) | 120.47 mi (193.87 km) |
| Sikeston to Calabasas (California) | 1,640.19 mi (2,639.63 km) |
| Sikeston to Caldwell (Idaho) | 1,493.93 mi (2,404.25 km) |
| Sikeston to Caledonia (Wisconsin) | 418.50 mi (673.51 km) |
| Sikeston to Calera (Alabama) | 305.53 mi (491.71 km) |
| Sikeston to Calexico (California) | 1,493.63 mi (2,403.77 km) |
| Sikeston to Calhoun (Georgia) | 308.87 mi (497.07 km) |
| Sikeston to California (Maryland) | 722.79 mi (1,163.21 km) |
| Sikeston to California City (California) | 1,579.33 mi (2,541.68 km) |
| Sikeston to Callaway (Florida) | 520.88 mi (838.27 km) |
| Sikeston to Calumet City (Illinois) | 344.35 mi (554.18 km) |
| Sikeston to Calverton (Maryland) | 703.95 mi (1,132.90 km) |
| Sikeston to Camano (Washington) | 1,828.86 mi (2,943.27 km) |
